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儿童的腹腔内压力测量:一项回顾性研究
Anne-Louise Sawaya1, Ivan Damgov2, Soraya Menouer3
1Service de pédiatrie 2, Hôpital de Hautepierre, Hôpitaux universitaires de Strasbourg, Strasbourg, France
概括
在接受腹腔透析 (PD) 的儿童中,腹腔内压 (IPP) 测量通常是可以接受的,但显示出很高的变化. 需要进一步的研究来将IPP与患者的结果相关联.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 儿科 儿科 儿科
- 透析是通过透析进行的.
背景情况:
- 腹膜透析 (PD) 需要个性化的治疗方案,以获得最佳的临床耐受性和充分性.
- 建议对腹腔内压力 (IPP) 进行测量,以确定最佳腹腔内透析体量 (IPV),但常规临床数据有限.
研究的目的:
- 评估常规腹腔内压力 (IPP) 测量的适用性和可变性,用于自动腹腔透析 (APD) 的儿童.
- 在儿科群体中评估IPP,腹腔内透析体积 (IPV) 和PD相关并发症之间的关系.
主要方法:
- 对21名患有稳定自动化PD的儿童每月655次IPP测量的回顾性分析.
- 在白天 (IPP1) 和夜间 (IPP2) 停留量期间使用各种透析液测量IPP.
- 测量结果与PD相关的并发症和Kt/V相关.
主要成果:
- 平均IPP为11.0±2.6cmH2O,在夜间停留期间 (IPP2) 与白天停留期间 (IPP1) 相比,观察到的值更高.
- 随着每体表面积 (BSA) 的填充量增加,IPP增加.
- 在单次填充体积测量时,观察到IPP的显著个体内和个体间变异性.
结论:
- 在被研究的儿科群体中,IPP值是可以接受的.
- 更高的填充量与更高的IPP相关.
- IPP变化的临床意义及其与患者结局的直接关系仍然不确定.
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