莫波克斯病毒毒素-施莱芬融合蛋白通过隔离STAT2抑制先天的抗病毒反应

Pearl Chan1, Zi-Wei Ye1, Wenlong Zhao1

  • 1School of Biomedical Sciences, The University of Hong Kong, Pokfulam, Hong Kong.

PubMed
概括

马普克斯病毒的毒素-schlafen (PoxS) 蛋白质通过隔离STAT2,阻断干扰素刺激的基因表达和促进病毒复制来阻碍宿主抗病毒防御. 这揭示了病毒免疫逃避的一个关键机制.

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