胃 siderosis:一个内镜诊断挑战
Anabella Cuestas1, Miriam Cuatrecasas2, María Glòria Fernández Esparrach3
1Gastroenterology and Endoscopy, Hospital Clínic Barcelona , Spain.
Revista espanola de enfermedades digestivas
|March 11, 2025
概括
口服铁补充剂可能会导致胃肠道问题,如胃 siderosis (GS). 停止铁补充剂导致慢性贫血患者GS病变的解决.
科学领域:
- 胃肠病学 胃肠病学
- 血液学 血液学 血液学
- 病理学 病理学 病理学
背景情况:
- 一名71岁的男性患有严重的血管疾病,膜病变和慢性溶血性贫血,提交检查.
- 该患者正在接受抗凝疗,并已服用口服硫酸铁二年来管理贫血.
研究的目的:
- 在患有多种并发病症的患者中调查持续性贫血的原因.
- 评估内镜和组织病理学发现,表明药物诱导的损伤.
主要方法:
- 进行上部胃肠道内镜 (UGE) 检查持续性贫血.
- 对观察到的病变进行了活检以进行组织病理学分析.
- 珀尔的铁染料被用来确认铁性颜料的存在.
主要成果:
- 超大脑检查显示了广泛的结节区域,有棕色沉积物和胃肠道上部的自发出血.
- 活检表明轻度炎症和铁性色素的存在,与药物诱导的损伤一致.
- 诊断为胃 siderosis (GS),并停止了补充铁的治疗.
结论:
- 口服铁补充剂可能导致胃 siderosis,一种形式的药物诱导的伤害.
- 停止铁补充剂导致GS病变的解决.
- 这一案例凸显了在患者中考虑药物副作用的重要性,这些患者有不明原因的胃肠道发现.
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