结核病感染在患有皮肤神经炎的患者
Luis Carlos Palomino Romero1, Alfredo Vargas Caselles1, Natalia Soledad Rius1
1Rheumatology Section, Internal Medicine Department, Italian Hospital of Buenos Aires.
Reumatismo
|March 11, 2025
概括
皮质神经炎患者容易感染感染. 三例患者患有结核性肌肉炎,由于症状与潜在的炎症状况重叠,因此存在诊断挑战.
科学领域:
- 传染性疾病 传染性疾病
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
背景情况:
- 皮肤肌肉炎 (DM) 患者因疾病及其治疗而经历免疫抑制.
- 这种免疫抑制增加了对机会性感染的易感性.
- 结核病 (TB) 可以在肌肉中表现出来,模仿炎症性肌肉病的症状.
研究的目的:
- 在被诊断为皮肤肌炎的患者中描述结核性肌炎的病例.
- 突出DM中结核病超级感染所带来的诊断挑战.
- 强调在DM恶化症的差异诊断中考虑结核病的重要性.
主要方法:
- 一系列病例描述了三名患有DM和结核性肌肉炎的患者.
- 诊断方法包括Mycobacterium结核病的聚合酶链反应 (PCR) 和Ziehl-Neelsen染色.
- 用肌肉活检和支气管支气管洗进行样本采集.
主要成果:
- 三名患有DM的患者被诊断出结核性肌肉炎.
- 在一个案例中,在死后的肌肉活检中,通过PCR检测出Mycobacterium结核病.
- 在其他情况下,Ziehl-Neelsen染色和PCR在支气管支气管洗和组织样本中确认了结核病.
结论:
- 结核性肌肉炎可能发生在患有皮肤肌肉炎的患者中.
- 结核病超级感染的症状可能类似于皮肤肌炎,使诊断复杂化.
- 不同诊断对于DM患者机会性感染的适当管理至关重要.
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