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对比增强对比度的乳房扫描和低能量的成像与或没有补充全乳房美国在乳腺癌检测中的比较
Joao V Horvat1, Tali Amir1, Gordon P Watt1
1From the Departments of Radiology (J.V.H., T.A., C.E.C., N.N., M.S.J., J.S.S.) and Epidemiology and Biostatistics (G.P.W.), Memorial Sloan Kettering Cancer Center, New York, NY.
与低能量 (LE) 图像单独相比或与补充超声波相比,对比增强乳腺癌检测率显著提高. 这种先进的成像技术提供了更高的癌症检测和提高了查设置中的活检准确性.
科学领域:
- 放射学 放射学是一门学科.
- 医疗成像医学成像
- 在瘤学瘤学.
背景情况:
- 增强对比度的乳房镜像 (CEM) 结合了低能耗 (LE) 图像,类似于全场数字乳房镜像 (FFDM),与重组图像突出了病变血管性.
- 补充全乳房超声波 (US) 提高了FFDM的癌症检测,但不是MRI.
研究的目的:
- 为了比较CEM,单独LE图像和LE图像与全乳房US在查期间检测乳腺癌的有效性.
主要方法:
- 一项前性研究涉及468名女性参与者,他们接受了查性乳房影像和全乳房美术.
- 放射科医生将CEM,LE图像和全乳房US图像分别解释,并以盲目的方式进行.
- 对灵敏度,特异性,正预测值 (PPV) 和异常解释率的统计分析.
主要成果:
- 与LE图像 (1000分之2.1),或LE图像与US (1000分之8.5) 相比,CEM显示癌症检测率显著更高 (17.1).
- 与单独的LE图像或与US图像相比,CEM还显示了更高的异常解释率 (18.6%) 和进行活检的PPV (PPV3为45.0%) 和更高的PPV.
- 活检推率最高的是CEM (42.7/1000).
结论:
- 与全乳房超声波相补充的低能量的图像或低能量的图像相比,对比增强的乳房造影显著改善了查期间的乳腺癌检测.
- CEM提供了增强的诊断性能,导致更准确的癌症识别和更少的不必要的活检.
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