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Updated: May 23, 2025

Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis
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频繁献血者的克隆性血液形成景观

Darja Karpova1,2,3,4,5, Hector Huerga Encabo6, Elisa Donato1,2,3

  • 1Division of Stem Cells and Cancer, German Cancer Research Center, Heidelberg, Germany.

Blood
|March 11, 2025
PubMed
概括

频繁献血不会增加克隆性血液形成 (CH) 的发生率. 然而,红色素 (EPO) 选择性地促进了在捐赠者体内具有特定DNMT3A突变的造血干细胞 (HSC) 的生长,揭示了新的进化压力.

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