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Updated: May 23, 2025

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在药物动力学建模中的量化下限下处理受审查数据的务实方法

Marie Wijk1, Roeland E Wasmann1, Karen R Jacobson2

  • 1Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

CPT: pharmacometrics & systems pharmacology
|March 11, 2025
PubMed
概括

在量化极限 (BLQ) 以下处理数据是准确药理动力学分析的关键. 方法M7+为精确但数值不稳定的M3方法提供了稳定可靠的替代方案,特别是在模型开发中.

关键词:
这不是nonmemem.审查 审查 审查概率是指可能发生的情况.参数估计的参数估计.人口的药理动力学

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