诊断和预防的过渡区的拉通在患者与希尔施普朗格病的疾病
Raj P Kapur1, Vinay Prasad2, Shruthi Srinivas3
1From the Departments of Laboratory Medicine and Pathology (Kapur) and Pediatric Surgery (Smith), Seattle Children's Hospital and University of Washington, Seattle.
Archives of pathology & laboratory medicine
|March 11, 2025
概括
准确的病理学报告对于希尔施普朗格病切除至关重要. 许多外科病理学报告错过了关键的过渡区发现,可能导致不完整的手术,需要改进的诊断方法.
科学领域:
- 儿科手术 儿科手术
- 胃肠道病理 胃肠道病理
- 手术瘤学手术瘤学
背景情况:
- 赫施普朗格病的手术涉及切除角质肠和过渡区.
- 准确的病理学对于诊断和预防不完全切除至关重要.
研究的目的:
- 确定病理学实践改善的领域,用于赫施普朗格病切除.
主要方法:
- 从25个机构的35个赫施普朗格病切除术中审查了手术病理学报告和组织学幻灯片.
- 评估近接边缘分析,样本采样,过渡区组织学报告,并将发现与原始报告进行比较.
主要成果:
- 切除的结节性肠长度仅在51%的病例中被记录下来.
- 在23%的病例中,使用手术内冷截面进行近距离边缘评估,而在一些病例中,错过过渡区的发现.
- 过渡区组织学存在,但在经术后评估的33%病例中没有报告.
结论:
- 病理学家需要更好地了解过渡区组织学.
- 实施改进的方法来准确和及时诊断过渡区特征是必要的.
- 提供了改善病理学实践在希尔施普朗格病管理方面的建议.
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