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Updated: May 23, 2025

Author Spotlight: Advancing Thymic Epithelial Cells and T-Cell Research with Human Thymic Organoids
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甲状腺作为身体基因表达的镜子

Geraldo A Passos1, Adriana B Genari2, Amanda F Assis2

  • 1Laboratory of Genetics and Molecular Biology, Department of Basic and Oral Biology, Ribeirão Preto School of Dentistry (FORP-USP), University of São Paulo, Ribeirão Preto, SP, Brazil. passos@usp.br.

Advances in experimental medicine and biology
|March 11, 2025
PubMed
概括

骨髓胸膜上皮细胞 (mTECs) 通过杂交基因表达 (PGE) 来表达外周组织抗原 (PTAs),这对中央耐受性至关重要. AIRE和FEZF2基因调节这个过程,影响自我非自我歧视和自身免疫性疾病的预防.

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