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Updated: May 23, 2025

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
08:32

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Published on: March 2, 2014

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未整合的HIV-1DNA通过其组分素结合域招募cGAS,以逃避天生的免疫力

Cyprien Jahan1, Lucie Bonnet-Madin1, Shinichi Machida2

  • 1Institut de Génétique Humaine, Laboratoire de Virologie Moléculaire, CNRS Université de Montpellier-UMR9002, Montpellier 34000, France.

Proceedings of the National Academy of Sciences of the United States of America
|March 11, 2025
PubMed
概括

人类免疫缺陷病毒1型 (HIV-1) 通过使cGAS无活化来逃避天生的免疫力. 这阻止了免疫系统在囊脱涂后识别病毒DNA,帮助病毒传播.

关键词:
艾滋病病毒 艾滋病病毒 艾滋病病毒cGAS 是一个气体.在这种情况下,染色染色素具有天生的免疫力.

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