在资源有限的环境中,使用圣乔治呼吸道问卷对慢性阻塞性肺病进行基于人口的查
William Checkley1,2, Mingling Yang3, Nicole M Robertson3
1Johns Hopkins University, Division of Pulmonary and Critical Care, School of Medicine, Baltimore, Maryland, United States.
American journal of respiratory and critical care medicine
|March 11, 2025
概括
圣乔治呼吸道问卷 (SGRQ) 有效地选慢性阻塞性肺病 (COPD). 将SGRQ与峰值呼气流 (PEF) 结合起来,可以在资源有限的环境中改善COPD的识别.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 螺旋测量对于诊断慢性阻塞性肺病 (COPD) 至关重要,但在全球范围内往往无法获得.
- 查问卷提供了一个潜在的解决方案,以弥合COPD的诊断差距.
研究的目的:
- 评估圣乔治呼吸道问卷 (SGRQ) 作为COPD查工具.
- 为了验证SGRQ的性能与螺旋计确认的COPD诊断相比.
主要方法:
- 这是一项涉及尼泊尔,秘鲁和乌干达40岁以上的1008名成年人进行的横截面研究.
- 参与者完成了SGRQ和支气管扩展前呼吸道峰值流量 (PEF).
- 通过使用支气管扩展后FEV1/FVC Z-score < -1.645;接受器运行特征曲线分析了SGRQ的歧视性表现来定义COPD.
主要成果:
- 螺旋计证实了COPD的患病率为9.5%.
- 在COPD查中,SGRQ显示曲线下的面积 (AUC) 为0.77.
- 将SGRQ与PEF结合起来显著改善了AUC,达到0.84,具有高灵敏度 (91%) 和负预测值 (98%).
结论:
- SGRQ是一种可行的COPD替代查工具.
- 整合SGRQ和PEF可以提高COPD风险识别,特别是在缺乏螺旋计的资源有限的地区.
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