危重病成年人超限制性输血门:我们准备好了下一步吗?
Caroline M Schaap1, Robert B Klanderman1, Anna-Linda Peters1
1Department of Intensive Care, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Transfusion medicine reviews
|March 11, 2025
概括
患有贫血的重症患者可能会容忍低于当前7g/dL值的血红蛋白水平. 个性化输血决策可以降低与输血相关的风险和成本.
科学领域:
- 关键护理医学 关键护理医学
- 血液学 血液学 血液学
- 输血医学 输血医学
背景情况:
- 贫血在危急病患者中很常见,其中25%接受了输血.
- 目前限制性血红蛋白 (Hb) 输血门为非出血重症患者的7g/dL.
- 输血带有风险 (例如,循环过载,急性肺损伤) 和昂贵.
研究的目的:
- 评估降低重症患者血红蛋白输血门的安全性和有效性.
- 探索在特定患者群体中是否可以容忍Hb水平低于7g/dL.
主要方法:
- 对各种患者群体的输血门和结果的现有文献的审查.
- 分析涉及急性血液稀释和拒绝输血患者的研究.
- 在较低Hb水平下,检查严重烧伤或血液学障碍患者的结局.
主要成果:
- 一些患者类别可以容忍Hb水平低于7g/dL,没有显著的器官缺血.
- 拒绝输血的患者通常保持Hb水平为5g/dL或更低,不良结果有限.
- 在研究组中,较低的Hb水平 (低于7g/dL) 与死亡率或发病率的增加并不一致.
结论:
- 目前重症患者的血红蛋白输血门为7g/dL,可能过高.
- 降低输血门是潜在的安全,可以降低输血相关的风险和成本.
- 对于重症患者,建议对输血决策采取个性化的方法.
相关概念视频
02:45Blood Transfusion and Agglutination
10.7K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
10.7K
01:15Blood Transfusion
457
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
457