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Updated: May 18, 2026

HPLC-based Assay to Monitor Extracellular Nucleotide/Nucleoside Metabolism in Human Chronic Lymphocytic Leukemia Cells
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使用光检测方法的快速和敏感的HPLC用于在肝脏显微体和大鼠血中量化塞尔珀卡提尼布:对药物相互作用研究的含义

Aref L Zayed1, Aysheh M Alshekhhossin1, Omar M Al Kilani1

  • 1Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
|March 11, 2025
PubMed
概括

一种新的HPLC-FLD方法量化了selpercatinib,揭示了人类中度新陈代谢和与德克萨米他和米瑞的潜在药物相互作用. 鼠肝显微体显示出作为人类新陈代谢研究模型的希望.

关键词:
德克萨米他是一种在HPLC-FLD中使用.肝脏显微体 肝脏显微体米瑞西丁是什么意思?塞尔珀卡提尼布是如何使用的

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An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment08:59

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