用脱水醇丰富的Juncus effusus提取物粉对老年人的认知和灵巧表现的有益作用:一项随机,双盲,安慰剂控制,并行组研究
Atsushi Takeda1, Kazuyuki Mizuyama2, Toshiyuki Fukuda3
1School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, Japan.
Nutrition (Burbank, Los Angeles County, Calif.)
|March 11, 2025
概括
用脱水醇丰富的Juncus effusus提取物,在老年人中改善了认知功能和灵敏度. 这项研究表明,对老年人的认知和运动技能有潜在的益处.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 药理学 药理学是指药理学的学科.
背景情况:
- 脱水醇在预防粉样β诱导的神经退行和小鼠内存缺陷方面表现有前途.
- 衰老与认知能力下降和运动灵敏度下降有关.
- Juncus effusus是一种具有潜在治疗功能的植物.
研究的目的:
- 为了研究Juncus effusus提取物富含脱水醇对老年人的认知和灵巧表现的影响.
- 为了评估这种提取物在老龄化人口中的安全性和有效性.
主要方法:
- 这是一项为期24周的随机,双盲,安慰剂控制,并行组研究.
- 41名老年参与者 (平均年龄69岁) 每天接受J. effusus提取物片或安慰剂.
- 认知功能被评估使用五Cog测试,和灵巧度被评估组装任务.
主要成果:
- 与安慰剂组相比,服用J. effusus提取物的参与者在线索回忆和时钟绘制任务中得分明显高.
- 测试组还在装配任务中表现显著提高了灵巧度.
- 在研究期间没有报告任何不良事件.
结论:
- 富含脱水醇的Juncus effusus提取物可以提高老年人的认知功能.
- 提取物似乎还可以改善老年人灵巧的运动.
- 这项研究提供了初步证据,证明J. effusus提取物对老年人认知和运动表现的有益影响.
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