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BMP9通过USP10/FOXO1/GPX4轴缓解铁积累引起的骨质疏松症

Yanran Huang1, Jun Zhang1, Yafei Zhu1

  • 1Department of Orthopaedic Surgery, Chongqing Municipal Health Commission Key Laboratory of Musculoskeletal Regeneration and Translational Medicine/Orthopaedic Research Laboratory, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.

Journal of advanced research
|March 11, 2025
PubMed
概括

由于铁的积累导致骨髓介质干细胞 (BMSCs) 功能障碍导致骨质疏松症. BMP9通过USP10/FOXO1/GPX4通路抑制铁,为铁引起的骨质疏松症提供了一种新的治疗策略.

关键词:
BMP9 BMP9 BMP9 BMP9 BMP9 BMP9 BMP9 BMP9 BMP9 BMP9 BMP9 BMP9 BMP9铁性化 (ferroptosis) 是一种铁的积累 铁的积累骨质疏松症是一种骨质疏松症.USP10 10美元的价格

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