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在接受过导管三门干预手术的患者中,右心力衰竭和死亡率
Edoardo Pancaldi1, Marianna Adamo1, Matteo Pagnesi1
1Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.
International journal of cardiology
|March 11, 2025
概括
在接受过导管三管干预严重三管吐的患者中,具有两个或更多的右心力衰竭标准会增加死亡风险. 程序成功改善了生存率,无论右心力衰竭状态如何.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 心脏衰竭管理的管理
背景情况:
- 严重的三回 (TR) 通常导致右心力衰竭 (RHF).
- 透导管三门干预 (TTVI) 为症状严重的TR提供了一个治疗选择.
- 预先存在的RHF对TTVI结果的影响需要进一步调查.
研究的目的:
- 为了评估临床RHF状态和严重TR的TTVI接受患者的死亡率之间的关联.
- 为了确定RHF是否影响成功的TTVI与失败的TTVI相比,成功的TTVI的生存益处.
主要方法:
- 来自TriValve国际注册表的数据分析,这是一项针对接受TTVI的重症TR患者的多中心研究.
- 患者根据RHF的临床标准 (住院治疗前,身体症状或高剂量利尿剂) 进行了分层.
- 一年全因死亡率是主要结果,使用Cox比例危险模型进行评估.
主要成果:
- 在498名具有完整RHF数据的患者中,10.8%没有RHF标准,26.7%有1个,48.2%有2个,14.3%有3个.
- 具有两个或两个以上RHF标准的患者有显著更高的1年死亡风险 (调整后HR2.91).
- 红射线状态没有影响手术成功与1年死亡率之间的关联 (p-相互作用 = 0.857).
结论:
- 存在至少两个临床标准的RHF是独立相关的增加1年死亡率在患者接受TTVI严重的TR.
- 成功的TTVI与死亡风险降低有关,无论患者的RHF状态如何.
- 对RHF的临床评估对于被考虑为TTVI的患者的风险分层至关重要.
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