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非液态矩阵生物分析的最佳实践和建议

Faye Vazvaei-Smith1, Wenkui Li2, Omar S Barnaby3

  • 1Merck & Co., Inc., West Point, Pennsylvania, 19486, USA. fataneh.vazvaei-smith@merck.com.

The AAPS journal
|March 12, 2025
PubMed
概括

本文提供了在药物开发中分析非液态矩阵 (NLM) 的基本最佳实践. 它解决了挑战,并为定量NLM生物分析提供了指导,以推进药物发现.

关键词:
在PK/PD中,PK/PD是最常见的.生物分析是一种生物分析.生物标志物 生物标志物细胞 细胞 细胞 细胞 细胞适用性验证 适用性验证溶解物质的溶解物质非液体矩阵的非液体矩阵.药物动力学 药物动力学组织组织组织组织组织.

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