基于EQ-VT和十字路口的EQ-5D-5L价值集的直接比较
Henry Bailey1,2, Bram Roudijk3,4
1Department of Economics, The University of the West Indies, St. Augustine Campus, St. Augustine, Trinidad and Tobago. hhbailey@gmail.com.
Applied health economics and health policy
|March 12, 2025
概括
使用跨行方法推导出的国家级EQ-5D-5L值集显示与基于EQ-VT的值集不太一致. 这些不同的价值集不应在健康经济学研究中互换使用.
科学领域:
- 卫生经济学 卫生经济学
- 心理测量 心理测量 心理测量
- 患者报告的结果
背景情况:
- 缺乏系统的国家级对步行者十字路口和EQ-VT衍生的EQ-5D-5L值集进行比较.
- 差异可能来自估值协议,不断变化的社会偏好,以及移动维度最高级别描述符的变化.
- 本研究解决了对这些价值设定方法的直接比较的需求.
研究的目的:
- 系统地比较通过步行交叉方法获得的国家级EQ-5D-5L价值集与使用EQ-VT (估值集工具) 方法生成的EQ-5D-5L价值集.
- 探索和量化这些两种不同的方法之间的差异,以获得不同国家的EQ-5D-5L值.
主要方法:
- 对比了19对EQ-5D-3L/EQ-5D-5L值组,这些值组来自拥有现有数据的国家.
- 从EQ-5D-3L数据开发了5L步行者十字路口集,并将它们与基于EQ-VT的国家EQ-5D-5L集进行了比较.
- 使用相关性分析,范围分析,特定状态值,布兰德-阿尔特曼图和散射图进行比较. 分析了三个国家与直接受访者数据单独.
主要成果:
- 斯皮尔曼相关性在0.831到0.989之间,其中11对低于0.9.
- 负值的差异在+22.5%至-18.8%之间,范围差异在+42.7%至-18.4%之间.
- 平均平均绝对差异为0.149,在19对中14对中超过0.1. 维度排名,特别是移动性,发生了显著的转变.
结论:
- 跨越越过路和基于EQ-VT的EQ-5D-5L价值集在多个标准之间表现出很差的一致性.
- 移动性维度的标签差异显著影响价值组的结果.
- 不建议互换使用行人交叉路口和EQ-VT值集,除非直接EQ-5D-5L估值是不可行的.
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