染色体重塑蛋白BPTF在平面干细胞中的基因促进器中调解染色体的可访问性

Prince Verma1, John M Allen1, Alejandro Sánchez Alvarado2

  • 1Department of Biology, University of Kentucky, Lexington, KY, USA.

BMC genomics
|March 12, 2025
PubMed
概括

原PHD指蛋白 (BPTF) 对于维持平面干细胞中的染色质可访问性至关重要,影响基因调节. 失去BPTF会影响促进体的可访问性,特别是对由Set1依赖的H3K4me3标记的基因,这揭示了它在干细胞稳态中的作用.

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