[补时接种疫苗可以预防HPV感染和相关的癌前症,如果在26岁之前接种]
Christina Carlander1, Christer Borgfeldt2, Lalle Hammarstedt Nordenvall3
1docent, överläkare, Karolinska universitetssjukhuset, Stockholm.
概括
针对26岁以下的男性进行人乳头瘤病毒 (HPV) 疫苗接种是具有成本效益的,对于预防HPV相关癌症至关重要. 疫苗接种还有助于减少HPV传播和实现群体免疫.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 疫苗学 疫苗学 疫苗学
背景情况:
- 与HPV相关的癌症,包括门癌和口腔喉癌,在瑞典和全球都呈现越来越高的发病率.
- 某些人群,如与男性发生性关系的男性,跨性别者和艾滋病毒感染者,面临特别高的风险.
- 接种HPV疫苗在预防HPV感染和相关癌前症方面是非常有效的,当给26岁以下的个人接种时.
研究的目的:
- 评估瑞典26岁以下未接种疫苗的男性接种HPV疫苗的成本效益.
- 突出需要癌查指南和提高高风险群体的查能力.
- 强调男性HPV疫苗接种的双重好处:通过减少传播和增强群体免疫力来保护个人和间接保护女性.
主要方法:
- 瑞典公共卫生署评估了追赶HPV疫苗接种计划的成本效益.
- 审查了国际指导方针,建议对高风险人群进行门癌症查.
- 评估了瑞典目前的查能力和指导方针的可用性.
主要成果:
- 瑞典公共卫生机构认为,在26岁以下未接种疫苗的男性接种HPV疫苗可能具有成本效益.
- 国际指导方针建议每年对高风险群体进行门癌查,年龄从35-45岁开始.
- 瑞典目前缺乏癌查的具体指导方针,查基础设施有限.
结论:
- 在男性中增加HPV疫苗接种覆盖率对于减少HPV相关癌症的负担至关重要.
- 在瑞典开发和实施有效的门癌查方法至关重要.
- 接种男性疫苗有助于群体免疫力,间接有利于妇女,并加速消除宫癌.
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