简单疹病毒的病例报告与腹膜透析腹膜炎相关,同时使用腹膜内环氧
Arti Dhoot1, Bourne Auguste1,2,3, Jenny Ng4
1Division of Nephrology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Kidney medicine
|March 12, 2025
概括
简单疹病毒 (HSV) 周周炎可能被误诊. 这一案例突出显示,在透析患者中,成功治疗HSV-2腹膜炎,使用腹膜内阿西克洛维尔,改善结果.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 传染性疾病 传染性疾病
- 病毒学 病毒学
背景情况:
- 病毒性腹膜炎,包括简单疹病毒 (HSV),由于透析废水中的病毒检测有限,经常被误诊为培养阴性腹膜炎.
- 这种诊断挑战可能会导致无效的抗生素治疗和过早的导管切除,因疑似耐火性周周炎.
研究的目的:
- 报告在接受连续循环腹膜透析的患者中成功治疗2型简单疹病毒 (HSV-2) 腹膜炎的病例.
- 为了突出腹膜内用阿西克洛维尔治疗病毒性腹膜炎的有效性.
主要方法:
- 一名73岁的女性患者接受腹膜透析,怀疑患有腹膜炎,呈现出特征性症状和淋巴细胞占主导地位的排泄物.
- 细菌和真菌培养是负的;然而,废水对HSV-2的检测结果呈阳性.
- 腹腔内用阿西克洛维尔是通过2.5%的迪安尼尔袋进行的.
主要成果:
- 患者在开始腹腔内阿西克洛维尔治疗后一周内显著改善了细胞计数.
- 在两周后重复的废水分析对HSV是负的.
- 这一案例代表了病毒性周周炎的成功治疗与腹腔内阿西克洛维尔.
结论:
- 病毒性腹膜炎应考虑在培养阴性腹膜炎的情况下,特别是在免疫功能低下的患者或具有相关暴露史的患者中.
- 内酸克洛维尔是一种可行的,有效的治疗方案,用于HSV腹膜炎,提供局部效应,并最大限度地降低全身毒性.
- 这一案例补充了病毒性腹膜炎的有限文献,并证明了一种新且成功的治疗方法.
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