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Updated: May 23, 2025

Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer
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乳腺癌临床前模型:理解疾病机制和治疗开发的重要资源

Ravneet Kaur1, Anuradha Sharma1, Nalaka Wijekoon2,3

  • 1Department of Molecular Biology and Genetic Engineering, School of Bioengineering and Biosciences, Lovely Professional University, Punjab-144411, India.

EXCLI journal
|March 12, 2025
PubMed
概括

选择适当的临床前乳腺癌模型对于药物发现至关重要. 本综述考察了各种模型,突出了它们的优缺点,以改善从实验室到临床的治疗转化.

关键词:
乳腺癌 乳腺癌 乳腺癌乳腺癌的种类 乳腺癌的种类临床前模型的临床前模型三重阴性乳腺癌是什么妇女的健康妇女的健康

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Mouse Models of Cancer Study02:43

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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