关于拉丁美洲艾滋病毒暴露前预防的最新情况:可用的药物和实施情况
Christian Gonzales-Gavancho1, Julieta M Araoz-Salinas1,2, Ruth Ramon Tapia3
1Peruvian American Medical Society (PAMS), Albuquerque, NM 87111, USA.
Le infezioni in medicina
|March 12, 2025
概括
暴露前预防 (PrEP) 可以防止艾滋病毒的传播,但在拉丁美洲的实施面临着重大障碍. 应对这些挑战至关重要,以减少不断上升的艾滋病毒感染率,并确保公平获得这一关键的预防工具.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 预防艾滋病毒/艾滋病 预防
背景情况:
- 拉丁美洲在2010年至2023年期间,新的艾滋病毒感染人数增加了9%.
- 暴露前预防 (PrEP) 是一种高效的生物医学干预措施,用于预防艾滋病毒.
- 现有各种PrEP配方,包括口服和注射抗逆转录病毒药物,证明了显著的疗效.
研究的目的:
- 突出在整个拉丁美洲实施PrEP的挑战.
- 识别阻碍 PrEP 广泛获取和使用的障碍.
- 强调需要创新的战略和政策改进,以公平地分配PrEP.
主要方法:
- 审查目前全球可用的PrEP选择及其有效性.
- 分析拉丁美洲的PrEP实施状况和获取差异.
- 确定PrEP获取的主要障碍,包括意识,资金和政策问题.
主要成果:
- 尽管可用的PrEP药物 (例如,emtricitabine/tenofovir,dapivirine环,cabotegravir,lenacapavir) 的高疗效,但在拉丁美洲的实施不均.
- 巴西,墨西哥和哥伦比亚等国家在采用PrEP方面取得了进展,但在区域范围内仍然存在重大差距.
- 诸如有限的认识,资金不足,政治不稳定和过时的政策等障碍妨碍了公平的获取.
结论:
- 迫切需要克服拉丁美洲PrEP的实施挑战,以应对不断上升的艾滋病毒率.
- 创新策略和政策改革至关重要,以确保所有处于风险人群都能获得PrEP.
- 解决系统性障碍对于减少艾滋病毒传播和实现该地区公共卫生目标至关重要.
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