移植患者的登革热:系统性审查
Andres Felipe Salazar-Urbano1,2, Otto Alberto Sussmann-Peña1,2, Jonathan Alexander Guezguan-Perez3
1Semillero de Investigación en Infectología Clínica, Infectoclínicos, SAS, Bogotá, DC, Colombia.
Le infezioni in medicina
|March 12, 2025
概括
在移植接受者 (KTR) 中的登革热感染发生的发病率是可变的,在60%以上的患者中报告了显著的全移植功能障碍. 在KTR早期查登革热对于管理这种普遍的并发症至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
- 移植手术 移植手术
背景情况:
- 全球范围内登革热的发病率和并发症正在上升,特别是在特有地区.
- 有限的数据存在于登革热的结果,特别是在移植接受者 (KTR).
研究的目的:
- 为了确定被诊断为登革热的KTR患者的发病率,临床表现和全移植功能障碍.
- 评估登革热感染对脏移植结果的影响.
主要方法:
- 根据PRISMA 2020指南进行了一次系统的文献审查.
- 包括到2023年11月24日发表的研究,分析了来自4337个KTR的数据,其中包括214例登革热病例.
主要成果:
- 在KTR中登革热的发病率为4.93%,区域差异很大.
- 发烧 (83.18%) 是最常见的症状. 移植功能障碍发生在63.08%的病例中,移植损失率为4.67%.
- 报告的死亡率为7.01%.
结论:
- 登革热感染在KTR中具有高异位移植功能障碍的高风险.
- 可变的发病率需要仔细考虑地理位置和查协议.
- 建议加强对捐赠者和移植候选人的查,以减轻与KTR的登革热相关的风险.
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