各种非药物干预措施的比较有效性,包括用于癌症相关认知障碍的基于传统中医的干预措施:一个全面的网络元分析
Mu-Hsing Ho1, Lizhen Wang1, Justin Wei Ho Wong1
1School of Nursing, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR.
Journal of the National Cancer Institute
|March 12, 2025
概括
这项研究发现,太极拳/青功对癌症患者的主观认知投诉和认知康复对于癌症患者的整体认知功能最好. 针点刺激也改善了特定的认知领域.
科学领域:
- 在瘤学瘤学.
- 综合医学是一个整体的医学.
- 认知神经科学 认知神经科学
背景情况:
- 与癌症相关的认知障碍是癌症及其治疗的常见并发症.
- 传统中医 (TCM) 对认知功能干预措施的有效性尚未得到充分研究.
- 这项研究重点关注非中枢神经系统癌症.
研究的目的:
- 为了比较各种非药物干预对癌症患者认知功能的有效性.
- 为了对改善主观和客观认知功能的最佳干预进行排名.
- 在比较分析中包括基于中国传统医学 (TCM) 的干预措施.
主要方法:
- 在PubMed,Embase,ProQuest,Scopus和CNKI数据库中进行系统搜索,直到2024年5月.
- 包括评估非药物干预的随机对照试验 (RCT).
- 网络元分析使用随机效应模型来评估认知功能的主要终点.
主要成果:
- 分析了84个涉及15项非药物干预的RCT,没有报告任何重大不良事件.
- 太极拳/青功显示了提高主观认知功能的最高概率 (SMD = 2.10).
- 认知康复在整体认知功能 (SMD=1.49),执行功能和语言方面排名最高. 针点刺激在视觉空间和运动功能方面表现出色 (SUCRA 84.3%).
结论:
- 太极拳/青功在癌症患者的主观认知投诉方面非常有效.
- 认知康复在包括执行功能和语言在内的客观认知领域提供了最全面的好处.
- 针点刺激是提高视觉空间和运动功能的主要干预措施.
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