从有或没有1型糖尿病的妇女的产前和产后胆乳的比较
Alexandra Goldberg1, Hans Pettersson1, Cecilia Ekéus2
1Department of Clinical Science and Education, Karolinska Institutet Soder Hospital, Stockholm, Sweden.
概括
母亲1型糖尿病不会改变胆乳中关键的宏观营养素,如碳水化合物,卡路里和脂肪. 然而,产前蛋白质含量有所不同,第一天乳酪与商业配方奶粉有所不同.
科学领域:
- 周围生理学 周围生理学
- 新生儿营养新生儿营养
- 内分泌学 在内分泌学.
背景情况:
- 对于患有1型糖尿病的母亲的新生儿来说,以补充胆乳或商业配方奶为补充养是常见的,以预防新生儿低血糖症.
- 关于1型糖尿病妇女的乳酪蛋白的特定宏观营养成分的研究有限.
研究的目的:
- 研究和比较怀孕期间和产后早期收集的母乳中的宏观营养素含量 (碳水化合物,蛋白质,脂肪,卡路里) 在患有和没有1型糖尿病的妇女中.
- 为了比较产后第一天的乳酪的营养状况与商业配方奶粉.
主要方法:
- 进行了一项包括20名女性 (10名患有1型糖尿病,10名没有) 的队列研究.
- 在妊娠第36-40周和产后第1-5天之间的10个时间点收集了乳头样本.
- 使用母乳分析仪测量了巨量营养素和千卡路里,通过线性混合模型和单样品t测试分析数据,以进行配方比较.
主要成果:
- 在患有和没有1型糖尿病的妇女之间,没有观察到胆汁碳水化合物,千卡路里或脂肪的显著平均差异.
- 在所有测试时间点 (p=0.01) 中,在产前蛋白质含量中发现了显著差异.
- 在分娩后的第一天,母乳中的巨量营养素与商业配方奶粉和大多数其他母乳收集点相比有所不同,除了38周的妊娠期外.
结论:
- 这项研究提供了关于1型糖尿病和没有1型糖尿病的女性产前和产后大乳液的宏观营养素概况的见解.
- 需要进一步的研究,以阐明补充养策略 (产前/产后乳酪与商业配方奶粉) 对新生儿低血糖的影响.
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