"便秘":一个词,在癌症患者中有许多含义:一项观察性研究
Andrew Davies1,2,3, Norah Fagan3, Jenny Power2,3
1School of Medicine, Trinity College Dublin, Dublin, Ireland.
Palliative medicine
|March 12, 2025
概括
对于晚期癌症患者来说,关于便秘的简单问题是不够的. 许多符合阿片类药物诱导便秘的罗马IV标准的患者没有自我报告症状,强调需要更好的评估策略.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 抚慰性护理是一种缓解性护理.
背景情况:
- 便秘是晚期癌症患者中普遍存在且负担重重的问题,往往管理不当.
- 现有的诊断标准,如罗马四号存在,但"便秘"的主观性质使评估和诊断复杂化.
研究的目的:
- 检查晚期癌症患者自我报告的便秘与他们遵守阿片类药物诱导便秘的罗马IV诊断标准之间的关联.
- 探索自我报告和标准遵守的人口统计差异.
主要方法:
- 在24个欧洲地点进行了一项多中心前性观察研究.
- 招募了1200名接受阿片类药物治疗疼痛的成人癌症患者.
主要成果:
- 虽然45.5%的人自我报告了便秘,59.5%的人符合阿片类药物诱导便秘的罗马四号标准.
- 相当多的人 (39%) 符合罗马四号标准,并没有自我报告便秘.
- 年龄和原籍国等人口因素影响了自我报告.
结论:
- 患者自我报告和客观的罗马IV标准之间存在显著的差异,用于晚期癌症中便秘.
- 唯一的问题是"你有没有便秘?" 对于准确的评估是不够的.
- 定期,全面的便秘评估对于服用阿片类止痛药的晚期癌症患者至关重要.
相关概念视频
Assessment of the Rectum and Anus
128
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
128
Chronic Bowel Disorders: Introduction
375
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
375
Drugs for Treatment of Constipation-Predominant IBS
124
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
124
Cancer Survival Analysis
315
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
315
Irritable Bowel Syndrome III: Medical and Nursing Management
133
Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
133
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
103
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
103


