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Updated: May 22, 2025

Studying RNA Interactors of Protein Kinase RNA-Activated during the Mammalian Cell Cycle
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Studying RNA Interactors of Protein Kinase RNA-Activated during the Mammalian Cell Cycle

Published on: March 5, 2019

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对调节哺乳动物细胞PD-1表达的RNA装置的结构研究

Jason R Stagno1, Justin C Deme2, Vibha Dwivedi1

  • 1Protein-Nucleic Acid Interaction Section, Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, United States.

Nucleic acids research
|March 12, 2025
PubMed
概括

工程RNA设备可以控制基因表达. 这项研究详细介绍了一种对四环素敏感的RNA装置 (D43),该装置调节免疫检查点蛋白PD-1,显示出癌症免疫治疗的潜力.

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