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少数民族儿童和患有糖尿病的青少年的高血糖紧急情况
Ahmed Badran1, Amruta Thakkar2, Despoina Galetaki3
1Department of Pediatrics, University of Utah Medical Center, Salt Lake City, Utah, USA.
Clinical pediatrics
|March 12, 2025
概括
在儿童中,混合糖尿病酸性酸症 (DKA) 和高血糖状态 (HHS) 是常见的. 识别这些混合病例对于尽量减少急性损伤和精神状态改变等并发症至关重要.
科学领域:
- 儿科 儿科 儿科
- 内分泌学 在内分泌学.
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 血糖过高的紧急情况,包括糖尿病酸性酸症 (DKA) 和超的高血糖状态 (HHS),是糖尿病的严重并发症.
- 混合呈现的DKA和HHS发生在显著比例的高血糖紧急情况.
- 了解这些表现在儿科患者群体中的独特特征和结果对于有效管理至关重要.
研究的目的:
- 描述患有高血糖紧急情况的儿科患者的临床特征,危险因素和结果.
- 为了比较儿童的DKA,混合DKA-HHS和HHS之间的特征和并发症.
- 突出承认混合DKA-HHS呈现的重要性.
主要方法:
- 一个15年的回顾性图表审查的儿科病人接受了高血糖紧急情况.
- 分析临床数据,包括人口统计,糖尿病类型,表现特征,治疗和结果.
- 在DKA,混合DKA-HHS和HHS组之间进行统计比较.
主要成果:
- 在322名患者中,83%患有DKA,16%患有混合DKA-HHS,1%患有HHS.
- 大多数DKA和混合DKA-HHS患者患有1型糖尿病 (T1DM),而HHS患者患有2型糖尿病 (T2DM).
- 与DKA组相比,混合DKA-HHS组显示出更高的静脉流体率,急性损伤 (AKI) 的几率增加,以及精神状态改变 (AMS). 在HHS患者中,AMS和AKI的发病率也很高.
结论:
- 混合DKA-HHS是儿科高血糖紧急情况的重要表现,特别是在T1DM中.
- 混合DKA-HHS和HHS与更高的AKI和AMS率有关,需要密集管理.
- 早期识别和适当管理混合DKA-HHS对于改善患者的治疗结果和降低发病率至关重要.
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