在医疗机构进行Candida auris查时需要考虑的关键因素:系统性审查
Anders Skyrud Danielsen1, Liz Ertzeid Ødeskaug1, Ragnhild Raastad1
1Department of Infection Control and Preparedness, Norwegian Institute of Public Health, Oslo, Norway.
Mycoses
|March 12, 2025
概括
黄菌的殖民可能会持续一年以上,主要是在沟和下皮肤上. 风险因素包括重症监护和侵入性设备,但对查指南的证据仍然有限.
科学领域:
- 医学真菌学 医学真菌学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 黄是一种多药耐药的真菌病原体,导致疫情爆发.
- 它殖民于皮肤和医院环境,对脆弱的患者构成风险.
- 目前在全球范围内正在制定预防指南.
研究的目的:
- 审查与Candida auris殖民或感染相关的因素的证据.
- 为了确定Candida auris殖民的持续时间和常见地点.
- 评估二次Candida auris病例的风险,以告知查.
主要方法:
- 在五个数据库中系统搜索初级研究和评论.
- 排除对治疗,管理,实验室方法,耐药性和环境查的研究.
- 从117项纳入研究中提取的数据的叙述总结.
主要成果:
- 殖民的持续时间可以超过一年,大和沟是主要的地点.
- 二次病例的风险各不相同,主要影响患者.
- 临床护理,侵入性设备,抗菌剂使用和并发症与殖民/感染有关.
结论:
- 在Candida auris查实践方面存在证据缺口.
- 大多数研究都是反应性的,在疫情爆发期间进行,缺乏系统的协议.
- 未来的查指南需要整合医学理论和酵母菌微生物学;严格的研究是必不可少的.
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