第一次重大下肢截肢的流行病学 - - 2010年至2021年的丹麦全国性队列研究
Anna Trier Heiberg Brix1,2, Katrine Hass Rubin3,4, Tine Nymark5,3
1Department of Orthopedic Surgery and Traumatology, Odense University Hospital, Odense, Denmark. anna.trier.heiberg.brix@rsyd.dk.
European journal of epidemiology
|March 12, 2025
概括
在丹麦,从2010年到2021年,主要下肢截肢 (MLEA) 的发生率有所下降,显著的转变是转截肢. 患者的并发症显示的变化很小,这表明手术策略的转变可能与患者的健康状况无关.
科学领域:
- 血管外科 血管外科
- 流行病学 流行病学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 主要下肢截肢 (MLEA) 是常见的外科手术程序.
- 了解MLEA手术策略和患者特征的趋势对于优化护理至关重要.
- 以前的研究没有全面描述MLEA发病率和外科手术方法的时间变化.
研究的目的:
- 分析2010年至2021年期间丹麦首次重大下肢截肢 (MLEA) 的发生率和手术策略.
- 描述患者的人口结构及其在研究期间的变化.
- 调查第一次MLEA手术水平的时间趋势.
主要方法:
- 通过使用来自丹麦国家患者登记册的数据,进行了一项全国范围的观察性登记册研究.
- 该研究包括2010年至2021年在18岁或以上的患者中进行的所有首次主要下肢截肢 (MLEA) 截肢.
- 进行了统计分析,以确定截肢发生率,手术水平和患者并发症的趋势.
主要成果:
- 总共有12,672名首次MLEA患者被确定. 年均MLEA发病率每年下降2.3%.
- 转截肢的数量显著增加 (每年10.9%),膝关节脱节的数量显著减少 (每年-19.4%) 和横截肢的数量显著减少 (每年-7.3%).
- 患者的并发症概况没有出现重大变化,尽管观察到失脂血症,功能衰竭,外围动脉疾病和心血管疾病的趋势.
结论:
- 在丹麦,首次主要下肢截肢 (MLEA) 的发生率正在下降,转移到关节截肢.
- 观察到的手术策略的变化与接受MLEA的患者的并发症概况的显著变化没有明显的关联.
- 需要进一步的研究来确定向更近端截肢水平的转变是否有利于患者的结果.
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