失衡的睡眠使死亡风险增加14-34%:一个元分析
Zoltan Ungvari1,2,3,4,5, Mónika Fekete6, Péter Varga6,7
1Vascular Cognitive Impairment, Neurodegeneration and Healthy Brain Aging Program, Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
GeroScience
|March 12, 2025
概括
睡眠时间短 (少于7小时) 和睡眠时间长 (9小时或更长) 都会增加成年人因任何原因死亡的风险. 观察到性别特异性差异,长时间睡眠对女性来说构成更大的风险.
科学领域:
- 流行病学 流行病学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 睡眠时间是健康的关键决定因素,但其与死亡率的确切关联需要进一步澄清.
- 现有的研究表明,睡眠不足和睡眠过多对长寿的影响存在矛盾.
研究的目的:
- 进行一项元分析,研究短时间和长时间睡眠时间与成年人全因死亡率之间的关系.
- 探索睡眠时间与死亡风险之间的关系中的潜在性别特异性差异.
主要方法:
- 在主要数据库 (PubMed,Cochrane Central,Web of Science) 进行了系统的文献搜索,直到2024年10月.
- 包括79个回顾性和前性队列研究,其中包括成人参与者和至少一年的随访.
- 使用随机效应模型计算了聚合危险比率,分组分析按性别和睡眠时间类别分层.
主要成果:
- 睡眠时间短 (<7小时) 与14%的死亡风险增加有关 (HR 1.14,95% CI 1.10-1.18).
- 长时间睡眠 (≥9小时) 与34%更高的死亡风险相关 (HR 1.34,95% CI 1.26-1.42).
- 这两种睡眠时间都增加了男性和女性的死亡风险,而长时间睡眠对女性的影响更为明显.
结论:
- 短时间和长时间的睡眠时间都与增加全因死亡率有显著的关联.
- 与睡眠时间相关的死亡风险的大小因性别而异.
- 研究结果强调需要在公共卫生倡议中考虑最佳睡眠时间,以长寿,并倡导性别特定的睡眠健康研究.
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