沙特阿拉伯利雅得的C型肝炎病毒的流行率和相关因素:一项大型跨部门研究
Nasser Alhaydar1,2, Raghib Abusaris3,4, Noof Alwatban1,5
1Department of Public Health, College of Public Health and Health Informatics, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Journal of epidemiology and global health
|March 12, 2025
概括
利雅得的C型肝炎病毒 (HCV) 患病率在2017-2022年期间为5.6%. 关键的风险因素包括男性性别,离婚/寡妇身份,糖尿病和高血压,突出了公共卫生干预的领域.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
- 公共卫生流行病学 流行病学
背景情况:
- 病毒性肝炎导致全球显著的死亡率,而C型肝炎病毒 (HCV) 由于其基因型和缺乏疫苗而构成越来越大的挑战.
- 直接作用抗病毒药物已经改变了HCV流行病学,但沙特阿拉伯的数据需要进一步调查有针对性的干预措施.
研究的目的:
- 在沙特阿拉伯的利雅得确定C型肝炎病毒 (HCV) 的终身患病率.
- 在研究人群中确定与HCV感染相关的人口和并发症因素.
主要方法:
- 一项横截面研究利用了利雅得一家三级医疗机构的患者数据库.
- 数据收集范围从2017年到2022年,包括所有接受查或被诊断患有HCV的个人.
- 分析重点关注与HCV感染相关的患病率,人口因素和并发症.
主要成果:
- 总共分析了16690名参与者,HCVRNA阳性率为5.6% (95%CI:5.2-5.9%).
- 与男性性别 (aOR:2.47),寡妇 (aOR:7.8) 或离婚 (aOR:2.07) 婚姻状况,糖尿病 (aOR:1.97) 和高血压 (aOR:2.87) 发现了显著的关联.
- 观察到每增加一年的感染几率增加 (aOR: 1.18) 和单个个体的风险降低 (aOR: 0.38).
结论:
- 该研究估计,在2017年至2022年期间,利雅得的HCV RNA阳性率为5.6%.
- 已确定的风险因素,如男性性别,寡妇/离婚者身份,糖尿病和高血压,为改善公共卫生策略提供了机会.
- 调查结果强调需要加强临床实践和有针对性的干预措施,以减少沙特阿拉伯的HCV负担.
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