探索睡眠模式与患有慢性焦虑症的年轻人早期心血管疾病标志物之间的联系
Jacob W Richardson1, Emily A Buck1, Jennifer B Weggen1
1Department of Kinesiology and Health Sciences, Virginia Commonwealth University, Richmond, Virginia, United States.
概括
睡眠不规则,而不是质量差,与慢性焦虑的年轻人心血管疾病风险有关. 不规则的总睡眠时间与较高的氧化压力,较差的血管功能和血压控制的减弱有关.
科学领域:
- 心血管科学 心血管科学
- 睡眠医学 睡眠医学
- 精神病学是一个精神病学.
背景情况:
- 慢性焦虑与睡眠不足和心血管疾病 (CVD) 风险增加有关.
- 睡眠障碍,包括质量和规律不佳,独立地与心血管疾病的发展有关.
研究的目的:
- 调查睡眠质量/规律性与慢性焦虑的年轻成年人早期心血管疾病风险指标之间的关联.
- 检查与睡眠模式有关的氧化应激,血管功能和血压控制.
主要方法:
- 在28名患有一般性焦虑障碍 (GAD) 或高GAD症状的年轻成年人中,评估了七天的睡眠质量 (总睡眠时间,睡眠效率) 和规律性 (标准偏差).
- 评估的心血管疾病前体:氧化应激,手臂动脉功能,微血管功能,运动压力反应和心血管巴罗反射灵敏度 (cBRS).
- 利用皮尔森的相关性来分析睡眠变量和心血管疾病前体之间的关系.
主要成果:
- 睡眠不规则 (SE-SD,TST-SD) 与氧化应激正相关.
- 不规则的总睡眠时间 (TST-SD) 与下臂动脉功能和cBRS有关.
- 睡眠质量指标 (TST,SE) 与心血管疾病前体没有显著的相关性.
结论:
- 慢性焦虑症患者的不规则的总睡眠时间与较高的氧化压力,较低的臂动脉功能和降低的血压控制 (较低的cBRS) 有关.
- 这些发现强调睡眠不规则是慢性焦虑的年轻成年人中心血管疾病前体发展的关键因素.
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