Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Neural Circuits01:25

Neural Circuits

Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
Cerebellum: Anatomical Regions01:17

Cerebellum: Anatomical Regions

The cerebellum, also known as the "little brain," is located in the posterior cranial fossa, inferior to the tentorium cerebelli and dorsal to the brainstem. It plays a significant role in motor control, coordination, and proprioception.
Cerebellar Structure
Externally, the cerebellum features a highly convoluted surface with numerous folia (narrow ridges) separated by shallow sulci (grooves). The cerebellum is divided into two hemispheres by a thin median structure known as the vermis. The...
Cerebrospinal Fluid01:21

Cerebrospinal Fluid

Cerebrospinal fluid (CSF) is a colorless liquid that flows around the brain and the spinal cord, playing a vital role in the protection, support, and overall function of the central nervous system (CNS). CSF production, circulation, and absorption are tightly regulated processes essential for the brain and spinal cord to function properly.
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain.
Clearance Models: Physiological Models01:09

Clearance Models: Physiological Models

Drug clearance is a critical pharmacokinetic process involving the irreversible removal of drugs from the body through various organs over a specified time period. Physiological models are indispensable in determining organ-specific clearance, defined by the proportion of the drug eliminated per unit of time from the organ's blood volume.
The organ's clearance rate depends on the blood flow to the organ and the extraction ratio (E). The extraction ratio describes the organ's proficiency in drug...
Model Approaches for Pharmacokinetic Data: Physiological Models01:15

Model Approaches for Pharmacokinetic Data: Physiological Models

Physiological models in pharmacokinetics are instrumental in understanding the distribution and elimination of drugs within the body. These models describe the drug concentration within target organs, influenced by factors such as drug uptake, tissue volume, and blood flow. Drug uptake is governed by the partition coefficient, which signifies the drug concentration ratio in tissue to that in the blood. The blood flow rate to a specific tissue is expressed as Qt, and the rate of change in tissue...
Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Comparison of safety and feasibility of on-clamp versus off-clamp robotic partial nephrectomy.

Urologia·2026
Same author

A frontotemporal dementia-like phenotype in schizophrenia: links to striatal dopamine and iron accumulation.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2026
Same author

Retinal nerve fibre layer thickness reflects characteristics of brain grey and white matter.

Imaging neuroscience (Cambridge, Mass.)·2026
Same author

Specific metabolic rate and body weight regulation: racial and ethnic differences in mass-independent energy expenditure.

Journal of endocrinological investigation·2026
Same author

Serum as an alternative to plasma for determining the ApoE4 phenotype using Pan-ApoE and ApoE4 chemiluminescent enzyme immunoassays.

Clinical chemistry and laboratory medicine·2026
Same author

From 'senile dementia' to NOVAS: the evolution of dementia classification.

Brain : a journal of neurology·2026

相关实验视频

Updated: May 12, 2026

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms
08:51

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms

Published on: November 1, 2019

5.6K

大脑大脑连接预测身体质量指数:一个新的开源的基于Python的框架用于基于connectome的预测建模.

Tobias Bachmann1, Karsten Mueller2,3, Simon N A Kusnezow4

  • 1Department of Neurology, University of Leipzig Medical Center, Leipzig 04103, Germany.

GigaScience
|March 12, 2025
PubMed
概括

肥胖会改变大脑与大脑之间的连接,影响认知功能. 与任务相关的大脑网络变化预测身体质量指数 (BMI),这表明与肥胖相关的认知缺陷的神经生物学基础.

关键词:
这就是为什么BMI是BMI.人类连接体项目 (HCP)在这里,Python是Python.小脑小脑是什么意思基于 connectome 的预测建模.功能磁共振成像 (fMRI) 是一种功能性磁共振成像.

更多相关视频

A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging
11:50

A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging

Published on: February 4, 2022

3.9K
Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

967

相关实验视频

Last Updated: May 12, 2026

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms
08:51

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms

Published on: November 1, 2019

5.6K
A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging
11:50

A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging

Published on: February 4, 2022

3.9K
Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

967

科学领域:

  • 神经科学是一个神经科学.
  • 认知神经科学 认知神经科学
  • 肥胖问题研究研究

背景情况:

  • 小脑,一个关键的大脑结构,显示肥胖的变化.
  • 肥胖会影响更高的认知功能,涉及大脑和大脑通路.
  • 调查身体质量指数 (BMI) 和大脑大脑连接之间的联系至关重要.

研究的目的:

  • 探索身体质量指数 (BMI) 和大脑大脑连接之间的关系.
  • 识别与BMI相关的特定大脑网络.
  • 了解与肥胖相关的认知障碍的神经生物学基础.

主要方法:

  • 利用了人类结合体项目的数据集 (fMRI,行为数据).
  • 使用基于连接组的预测建模 (CPM) 进行大脑大脑连接.
  • 开发了一个开源的Python框架,用于带有交叉验证的数据驱动分析.

主要成果:

  • 大脑和大脑连接性显著预测了BMI.
  • 任务通用连接是比休息状态或个人任务fMRI更可靠的BMI预测器.
  • 预测网络与前端对象,体运动,突出和默认模式网络重叠.
  • 在BMI预测和认知预测网络之间观察到一个反向的重叠.

结论:

  • 肥胖与大脑和大脑连接的特定变化有关,特别是在执行任务时.
  • 这些变化意味着大脑网络对于任务执行至关重要.
  • 这些发现表明,肥胖如何对认知任务表现产生不利影响的神经生物学基础.