相关实验视频

Updated: Jun 26, 2026

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Published on: March 31, 2021

脂质纳米载体含有eugenol用于假牙卫生:对Candida生物膜的疗效评估

Irisvaldo Lima Guedes¹, Matheus Oliveira do Nascimento², Leandro de Sousa Dias³

¹Universidade Federal do Piauí, Programa de Pós-Graduação em Odontologia (PPGO), Teresina, Piauí, Brasil.

Journal of applied oral science : revista FOB

|March 12, 2025

概括

这项研究开发了一种新的基于eugenol的纳米结构配方,用于假牙卫生. 该配方有效地减少了Candida生物膜,为假牙消毒提供了一个有前途的解决方案.

科学领域:

生物材料科学生物材料科学
纳米技术纳米技术
口腔微生物学口腔微生物学

背景情况:

* 虫菌种在假牙佩戴者中普遍存在,导致感染.
*欧根醇对菌有效,但溶解性差,挥发性高.
*纳米结构脂质载体 (NLCs) 提供了一种解决方案,可以在假牙卫生中提供eugenol.

研究的目的:

* 开发一种新型的消毒分散剂,用于牙套卫生,使用带有欧原醇的NLC.
*为了评估这种配方对Candida spp.的疗效. 生物片.生物片.

主要方法:

*使用超声波制备带有尤金醇的NLC (NFE).
* 特性包括粒子大小,PDI,泽塔电位和封装效率.
* 对Candida albicans和Candida glabrata生物膜进行了抗真菌活性评估.

主要成果:

* NFE纳米粒子具有最佳尺寸 (199.5nm),高均性和高封装效率 (83.07%).
*与自由尤根醇相比,NFE显示出明显较低的最小抑制度 (MIC).
*与对照组相比,NFE显示Candida生物膜的显著减少.

结论:

*开发的NFE配方具有针对Candida菌株的杀菌活性.
* NFE显著降低了Candida生物膜,这表明它有潜力在八小时内进行有效的假牙消毒.

更多相关视频

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms

Published on: September 16, 2022

Author Spotlight: Exploring Photodynamic Therapy with Curcumin in a Murine Model for Oral Candidiasis

Author Spotlight: Exploring Photodynamic Therapy with Curcumin in a Murine Model for Oral Candidiasis

Published on: October 27, 2023

相关概念视频

The Oral Microbiota

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...