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拉丁美洲的辅助生殖技术:拉丁美洲注册,2021年
Fernando Zegers-Hochschild1,2, Javier A Crosby1,2, Carolina Musri1,3
1Program of Ethics and Public Policies in Human Reproduction, Faculty de Medicine, University Diego Portales, Santiago, Chile.
JBRA assisted reproduction
|March 12, 2025
概括
新技术正在改善拉丁美洲的辅助生殖技术 (ART) 的有效性. 增加单个胚胎转移和囊胚使用显示出积极的结果,尽管双胞胎出生和围产死亡率需要注意.
科学领域:
- 生殖医学和内分泌学.
- 在体外受精 (IVF) 和胚胎学.
- 公共卫生和流行病学
背景情况:
- 拉丁美洲国家对辅助生殖技术 (ART) 的使用情况有很大差异.
- 寻求ART服务的老年患者人口是一个显著的人口趋势.
- 人们越来越重视先进的生殖技术和胚胎选择.
研究的目的:
- 分析2021年拉丁美洲ART利用和技术采用的趋势.
- 评估新技术对ART有效性和安全性结果的影响.
- 识别在ART获取和实践中的区域差异.
主要方法:
- 来自16个拉丁美洲国家的204所认可机构的跨国循环数据的回顾性分析.
- 数据收集集中在2021年启动的ART程序上.
- 统计分析以基于患者人口统计,程序和使用的技术来比较结果.
主要成果:
- 超过127,000个ART周期导致超过22,000个分娩,周期利用的区域差异很大.
- 40岁以上接受ART的女性比例增加,加上单个胚胎移植 (42.4%) 和胚胎细胞移植 (79.3%) 的增加.
- 与冷胚胎转移相比,在新鲜的胚芽细胞选择性单个胚胎转移中观察到更高的分娩率;植入前遗传测试显示,老年妇女的结果改善,流产率降低.
结论:
- 系统地收集跨国ART数据有助于合作发展和基于证据的生殖健康保健决策.
- 诸如胚胎细胞移植和植入前遗传检测等技术进步正在提高ART的成功率.
- 需要持续监测以解决差异并优化ART安全性,特别是在多胎妊娠和围产死亡率方面.
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