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全球创新网络 (WIN) 个性化癌症医学联盟:为患者带来下一代精确瘤学

Wafik S El-Deiry^1,2, Catherine Bresson¹, Fanny Wunder¹

¹Worldwide Innovative Network (WIN) Association - WIN Consortium, Chevilly-Larue, France.

|March 12, 2025

概括

全球创新网络 (WIN) 联盟通过使用人工智能和分子瘤板来指导N-of-1试验,推进精确瘤学,证明患者从向癌症治疗中受益.

科学领域:

基因组医学是基因组医学.
在瘤学瘤学.
生物信息学是一种生物信息学.

背景情况:

人类基因组项目启动了基因组医学时代,使得向癌症治疗成为可能.
精密瘤学旨在尽量减少无效的治疗方法和减少毒性,包括财务和时间负担.
全球创新网络 (WIN) 联盟成立,旨在推动个性化癌症医学的创新和合作.

研究的目的:

通过N-of-1分子驱动研究来证明患者从精密治疗中获益.
开发下一代精确瘤学试验,采用先进技术和多样化的患者群体.
解决精密瘤学的挑战,包括药物获取,成本和监管障碍.

主要方法:

使用转录学签名和人工智能 (AI) 算法.
在国际分子瘤委员会 (MTB) 的投入下进行全球精确癌症药物临床试验.
使用N-of-1分子驱动研究来评估患者从精密治疗中获益.

主要成果:

通过N-of-1研究,WIN成功地证明了患者从精密治疗中获益.
目前正在开发WIN下一代精密瘤学 (WINGPO) 试验,用于各种癌症环境.
WIN与各种利益相关者合作,以克服精确瘤学的挑战.

结论:

WIN的方法加速了精确瘤护理的未来.
合作努力对于推进全球个性化癌症治疗至关重要.
基于全面的OMIC数据的AI和MTB导向试验将指导晚期癌症的治疗选择.

关键词:

人工智能算法的人工智能算法没有1的篮子试验.数字病理学数字病理学获取毒品的机会是可以获得的.精确瘤学精确瘤学

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