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儿童的中央听觉处理受到围产期艾滋病毒暴露的影响
Peter Torre1, Haley Elliott2, Jennifer Shinn3
1From the School of Speech, Language, and Hearing Sciences, San Diego State University, San Diego, California.
The Pediatric infectious disease journal
|March 12, 2025
概括
与未暴露,未感染 (HUU) 儿童相比,患有围产期艾滋病毒 (PHIV) 的儿童表现出较差的中央听觉功能,特别是双耳整合. 患有围产期艾滋病毒暴露但未感染 (PHEU) 的儿童的结局与HUU儿童相似.
科学领域:
- 儿科听力学 儿科听力学
- 神经科学是一个神经科学.
- 传染性疾病 传染性疾病
背景情况:
- 艾滋病毒感染儿童面临听力损失的风险增加.
- 对于患有围产期艾滋病毒 (PHIV) 和围产期艾滋病毒暴露但未感染 (PHEU) 的儿童中中央听觉功能的理解有限.
研究的目的:
- 研究PHIV和PHEU儿童的中央听觉功能,特别是双耳集成,与未接触HIV,未感染 (HUU) 儿童相比.
- 评估艾滋病毒暴露对儿童听觉处理的影响.
主要方法:
- 在"艾滋病毒感染儿童的听觉研究"研究中,对268名儿童 (年龄在11-14岁) 进行了二维数字测试 (DDT).
- 测量每个耳朵的百分比正确度的DDT分数,作为综合性听力评估的一部分,评估了双耳整合.
主要成果:
- 与HUU儿童相比,在对共变量进行调整后,PHIV儿童在右耳 (8点下降) 和左耳 (15点下降) 均表现出明显较低的DDT得分.
- 患有PHEU的儿童的双边DDT分数略低于HUU儿童.
- 在患有PHIV的儿童中,HIV疾病变量和DDT结果之间没有发现显著的关联.
结论:
- 中央听觉功能,包括双耳集成,需要对艾滋病毒感染儿童进行评估.
- 与HUU儿童相比,患有PHIV的儿童在双耳一体化方面表现较差.
- 双耳整合障碍可能会对儿童的听力表现和学业成绩产生负面影响.
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