通过皮肤间的电神经刺激来进行神经肌肉激活的计算建模,用于背部下部的电神经刺激
Mohigul Nasimova1,2, Niranjan Khadka1, Marom Bikson1
1Department of Biomedical Engineering, The City College of New York, NY, United States of America.
Biomedical physics & engineering express
|March 12, 2025
概括
通过皮肤进行电神经刺激 (TENS) 治疗背部疼痛,可向肌肉深处输送大量电流,超过8厘米. 电极的位置,而不是形状,影响电流深度,支持TENS.
科学领域:
- 生物医学工程 生物医学工程
- 神经科学是一个神经科学.
- 物理疗法物理治疗
背景情况:
- 穿皮电神经刺激 (TENS) 是一种常见的治疗急性和慢性背痛的方法.
- TENS的有效性与电流透到组织的深度有关.
- 了解电流分布对于优化TENS疗效和患者结果至关重要.
研究的目的:
- 为了比较TENS期间电流流的强度和空间范围,在人背上使用各种电极位置和形状.
- 研究解剖学变化和电极配置对电流透深度的影响.
主要方法:
- 开发了一个高分辨率的MRI-derived人体背部的解剖模型,包括皮肤和肌肉部分.
- 模拟的TENS具有不同的电极位置 (上/下背部) 和形状 (方形,圆形,矩形),使用50mA电流.
- 分析了相对于神经肌肉激活值的电场强度和空间分布.
主要成果:
- 模拟的TENS条件导致电场在皮肤的高值和肌肉区域的中值都超过了.
- 在所有模拟的TENS条件下,电流透到背部组织超过8厘米,表明深层组织激活.
- 电极形状对深层组织电流透的影响最小;解剖学因素影响了肌肉激活.
结论:
- 模拟显示TENS期间大量电流透到深层肌肉层,支持神经和肌肉的激活.
- 解剖学精确的建模显示,TENS可以有效地刺激深层组织,这可能解释了背痛的临床益处.
- 研究结果表明,优化电极放置是最大化TENS治疗中治疗电流输送的关键.
相关概念视频
01:33Somatosensation
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
01:16Sensory Functions of the Skin
The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...