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Updated: May 22, 2025

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
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在登革热感染期间,CD4 T细胞占据了中心地位

Elsa Gomez-Escobar1, Naglaa H Shoukry2

  • 1Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada; Département de microbiologie et immunologie, Université de Montréal, Montréal, QC, Canada.

Cell reports
|March 12, 2025
PubMed
概括

研究人员在严重登革热患者中发现了一种特定的CD4 T细胞子集 (CXCR5-PD-1+). 这些细胞通过IL-21支持B细胞反应,并可以成为细胞毒性CD4T细胞.

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