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Updated: May 22, 2025

Dissecting Cell-Autonomous Function of Fragile X Mental Retardation Protein in an Auditory Circuit by In Ovo Electroporation
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在脆弱X综合征中大脑网络的改变

Flavia Venetucci Gouveia1, Jürgen Germann2, George M Ibrahim3

  • 1Neuroscience and Mental Health, The Hospital for Sick Children, Canada.

Neuroscience and biobehavioral reviews
|March 12, 2025
PubMed
概括

脆弱X综合征 (FXS) 涉及FMR1基因突变,导致大脑网络中断. 这些变化会影响认知和行为,研究强调神经代谢失衡和基因与大脑的相关性.

关键词:
认知缺陷 认知缺陷在FMR1基因中,脆弱X综合征 (FXS) 是一种疾病.基因-大脑-行为相互作用神经成像是一种神经成像.静止状态网络 (RSN) 是一个静止状态网络.治疗目标 治疗目标

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The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
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