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Updated: May 22, 2025

Two-photon Imaging of Intracellular Ca2+ Handling and Nitric Oxide Production in Endothelial and Smooth Muscle Cells of an Isolated Rat Aorta
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Published on: June 10, 2015

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对与人类RAAS基因相关的非同义SNP的计算和分子见解:对高血压脆弱性的后果

Jeyanthi Sankar1, Beena Briget Kuriakose2, Amani Hamad Alhazmi3

  • 1Department of Bioinformatics, Pharmacogenomics and CADD Lab, Alagappa University, Karaikudi, Tamil Nadu, India.

Journal, genetic engineering & biotechnology
|March 12, 2025
PubMed
概括

像AT1R,AT2R和MasR这样的RAAS基因中的遗传变异可以影响高血压风险. 这项研究确定了几种有害的误解变异,影响蛋白质结构和功能,可能有助于诊断和治疗开发.

关键词:
候选基因是一个候选基因.毒品的目标是毒品.人类健康 人类健康 人类健康在高血压的高血压.药物基因组学 药物基因组学多态性多态性多态性nsSNPs的预测结果

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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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