Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Skin Cancer01:30

Skin Cancer

3.0K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
3.0K
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

2.7K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
2.7K
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

4.9K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
4.9K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Spatial transcriptomic atlas of aggressive osteosarcomas reveals shared immune landscape and targetable surface markers.

Nature communications·2026
Same author

Avoiding Cisplatin-Related Hearing Loss, Including Implementing Sodium Thiosulfate as Otoprotectant Into Daily Pediatric Clinical Practice: Proceedings Based on Evidence and Expert Opinion From the Ototoxicity Taskforce of the SIOP Supportive Care Network.

Ear and hearing·2026
Same author

European guideline for imaging of primary paediatric and adult osteosarcoma and Ewing sarcoma: systematic review and joint statement by the FOSTER consortium, Euro Ewing Consortium, European Society of Paediatric Radiology, and the European Association of Nuclear Medicine.

The Lancet. Oncology·2026
Same author

MiT fusions, TSC1-TSC2 divergence, and stem-like programs reveal distinct origins and vulnerabilities in PEComa.

Nature communications·2026
Same author

Validation of the Transcription Association Chromosomal Instability Index Biomarker on RNA Sequencing in Soft Tissue Sarcomas.

JCO precision oncology·2026
Same author

Critical appraisal of patient-reported and clinician-reported outcome measures assessing functional outcomes in lower extremity bone sarcoma patients-a COSMIN-based systematic review.

Journal of patient-reported outcomes·2026

相关实验视频

Updated: May 22, 2025

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis
12:03

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis

Published on: December 9, 2016

12.4K

原发性皮肤/皮下尤文斯肉瘤

Thibaud Valentin1, Sarah Winter2, Valentine Martin3

  • 1Medical Oncology, Oncopole Claudius Regaud, Toulouse, France.

Bulletin du cancer
|March 12, 2025
PubMed
概括
此摘要是机器生成的。

皮肤/皮下尤文肉瘤瘤家族 (EFST) 是罕见的,小瘤. 局部EFST具有良好的预后,具有量身定制的化疗和手术,而转移性疾病需要密集治疗.

关键词:
化疗 化疗是一种化学疗法.化学疗法是一种化学疗法.尤文肉瘤 (Ewing Sarcoma) 是一种癌症.骨外的说法 骨外的说法这是一种外骨的外观.萨尔科姆·德温格 (Sarcome d'Ewing) 是一个著名的医生.这就是苏斯皮肤.皮下使用 皮下使用 皮下使用

更多相关视频

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies
07:15

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies

Published on: July 28, 2020

9.5K
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

1.0K

相关实验视频

Last Updated: May 22, 2025

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis
12:03

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis

Published on: December 9, 2016

12.4K
A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies
07:15

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies

Published on: July 28, 2020

9.5K
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

1.0K

科学领域:

  • 在瘤学瘤学.
  • 病理学 病理学 病理学
  • 手术瘤学手术瘤学

背景情况:

  • 皮肤/皮下尤宁肉瘤瘤家族 (EFST) 是罕见的,来自表面组织的独特实体.
  • 这些瘤的特点是特定的临床表现,通常比经典的尤文肉瘤小,偏爱远端,干部和头部/部位置.

研究的目的:

  • 确定皮肤/皮下欧文肉瘤瘤家族的诊断和治疗策略.
  • 根据瘤大小和转移状态概述预后因素和量身定制的治疗方法.

主要方法:

  • 发表文献和ESMO软组织瘤指南的审查.
  • 重点是用于诊断和分子确认 (EWSR1重组) 的核心针活检.
  • 讨论新辅助剂/辅助剂化疗,手术管理,以及用于分期的成像.

主要成果:

  • 局部EFST (<200mL) 可以使用不那么强烈的化疗方案 (例如圣朱德疗法) 来治疗,以尽量减少毒性.
  • 较大的瘤可能需要使用经典的VDC/IE协议.
  • 转移性EFST的预后不好,类似于经典的尤文肉瘤,需要积极的管理.

结论:

  • EFST需要在专业中心进行管理,采用多学科的方法.
  • 治疗应平衡治愈能力,尽量减少急性和晚期毒性,特别是在局部疾病中.
  • 进行手术切除是局部控制的首选,目的是尽可能避免放射治疗.