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Updated: May 22, 2025

Detection of Trypanosoma brucei Variant Surface Glycoprotein Switching by Magnetic Activated Cell Sorting and Flow Cytometry
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Detection of Trypanosoma brucei Variant Surface Glycoprotein Switching by Magnetic Activated Cell Sorting and Flow Cytometry

Published on: October 19, 2016

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非洲试管体中抗原表达层次的基因组决定因素

Zhibek Keneskhanova1,2, Kirsty R McWilliam1,2,3, Raúl O Cosentino1,2

  • 1Division of Experimental Parasitology, Faculty of Veterinary Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.

Nature
|March 13, 2025
PubMed
概括

病原体的免疫逃避依赖于抗原变异. 这项研究揭示了Trypanosoma brucei单细胞中的基因组重组如何决定抗原切换机制,这取决于DNA修复模板的可用性.

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