Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Reproductive Cloning01:27

Reproductive Cloning

29.9K
Reproductive cloning is the process of producing a genetically identical copy—a clone—of an entire organism. While clones can be produced by splitting an early embryo—similar to what happens naturally with identical twins—cloning of adult animals is usually done by a process called somatic cell nuclear transfer (SCNT).
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic...
29.9K
Asexual Reproduction02:38

Asexual Reproduction

29.7K
Asexual reproduction allows plants to reproduce without growing flowers, attracting pollinators, or dispersing seeds. Offspring are genetically identical to the parent and produced without the fusion of male and female gametes.
29.7K
Cloning of Dolly the Sheep01:08

Cloning of Dolly the Sheep

3.3K
The first successfully cloned mammal was Dolly, a sheep, born on 5th July 1996 at Roslin Institute, Scotland. The cloned sheep was named after the American singer Dolly Parton. Dolly lived for seven years and died of respiratory complications, which is speculated to be due to the actual age of her DNA. Because the DNA in cloned cells belongs to an older individual,  the cloned individual’s life expectancy may be affected. Indeed, analysis of Dolly’s DNA revealed shorter...
3.3K
Introduction to Nuclear Reprogramming01:14

Introduction to Nuclear Reprogramming

1.9K
Nuclear reprogramming is the process of switching gene expression of one cell type to that of another cell type, usually from a differentiated cell state to an undifferentiated cell state. Differentiation occurs during processes such as development and morphogenesis, tissue regeneration, and malignancy. Cells can also be artificially induced to reprogram their gene expression by techniques such as nuclear transfer, induced pluripotency, and cell fusion. Such techniques have many applications in...
1.9K
Binary Fission01:20

Binary Fission

54.9K
Fission is the division of a single entity into two or more parts, which regenerate into separate entities that resemble the original. Organisms in the Archaea and Bacteria domains reproduce using binary fission, in which a parent cell splits into two parts that can each grow to the size of the original parent cell. This asexual method of reproduction produces cells that are all genetically identical.
54.9K
Crossing Over01:34

Crossing Over

143.2K
Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I, where each chromosome—replicated in S phase—is now composed of two sister chromatids (identical copies) joined centrally.
The homologous pairs of sister chromosomes—one from the maternal and one from the paternal genome—then begin to align alongside each other lengthwise, matching corresponding DNA positions in a process...
143.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Contemporary Approaches Towards the Optimization of Embryo Implantation.

Journal of clinical medicine·2026
Same author

Protecting the health of donor-conceived offspring.

Familial cancer·2026
Same author

Trans-Phylum Single Cell Orthology Reveals Conserved Ovarian Cell States Between Sea Urchin and Human.

Genome biology and evolution·2026
Same author

The National Physician Shortfall: Congress Steps Into the Breach.

The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association·2026
Same author

Stem-Cell Medicine: Unlimited Possibilities.

Journal of general internal medicine·2026
Same author

CRISPR-Cas9 therapy: expanding possibilities.

The American journal of the medical sciences·2026
Same journal

Fucoxanthin Ameliorates Polycystic Ovary Syndrome by Coordinated Modulation of NF-κB and Nrf2 Signaling: Evidence from a DHEA-Induced Mouse Model.

Reproductive sciences (Thousand Oaks, Calif.)·2026
Same journal

Comparison of Fetal Cardiac Function in Structurally Normal Fetuses Conceived Via IVF and Spontaneous Pregnancy: a Prospective Case-Control Study.

Reproductive sciences (Thousand Oaks, Calif.)·2026
Same journal

The Pathogenesis of Preeclampsia: Hypoxia and the Unfolded Protein Response.

Reproductive sciences (Thousand Oaks, Calif.)·2026
Same journal

Therapeutic Effects of Adipose-Derived Mesenchymal Stem Cell Exosome like Nanovesicles on Granulosa Cell Function in a Mouse Model of Polycystic Ovarian Syndrome: Involvement of FOXO3, Map1lc3b, SF-1 Genes.

Reproductive sciences (Thousand Oaks, Calif.)·2026
Same journal

Mincle Receptor Deficiency Protects Against LPS-induced Preterm Birth and Fetal Inflammatory Response Syndrome.

Reproductive sciences (Thousand Oaks, Calif.)·2026
Same journal

A Risk Score for Polycystic Ovary Syndrome Based on Meta-Analysis and Machine Learning of Gut Microbiota Signatures.

Reproductive sciences (Thousand Oaks, Calif.)·2026
查看所有相关文章

相关实验视频

Updated: May 22, 2025

Manipulation of Ploidy in Caenorhabditis elegans
07:54

Manipulation of Ploidy in Caenorhabditis elegans

Published on: March 15, 2018

10.9K

复制是 (重新) 定义的.

Eli Y Adashi1, Gary M Wessel2

  • 1Division of Biology and Medicine, Department of Molecular and Cellular Biology & Biochemistry, Brown University, 185 Meeting Street, Providence, RI, 02912, USA.

Reproductive sciences (Thousand Oaks, Calif.)
|March 13, 2025
PubMed
概括
此摘要是机器生成的。

体细胞核转移和诱导多能干细胞为创造功能性性子细胞提供了新的途径. 然而,这些方法使用体细胞,挑战了发育生物学中已建立的韦斯曼屏障概念.

更多相关视频

The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan
11:58

The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan

Published on: June 29, 2018

8.6K
Recombineering Homologous Recombination Constructs in Drosophila
14:23

Recombineering Homologous Recombination Constructs in Drosophila

Published on: July 13, 2013

19.1K

相关实验视频

Last Updated: May 22, 2025

Manipulation of Ploidy in Caenorhabditis elegans
07:54

Manipulation of Ploidy in Caenorhabditis elegans

Published on: March 15, 2018

10.9K
The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan
11:58

The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan

Published on: June 29, 2018

8.6K
Recombineering Homologous Recombination Constructs in Drosophila
14:23

Recombineering Homologous Recombination Constructs in Drosophila

Published on: July 13, 2013

19.1K

科学领域:

  • 生殖生物学 生殖生物学
  • 发育生物学是发展生物学.
  • 细胞重新编程的细胞重编程.

背景情况:

  • 韦斯曼屏障是生物学的一个基本概念,它假定了从生殖细胞到体细胞的基因信息的单向流动.
  • 细胞重编程和核转移技术的近期进展为从体细胞中生成子细胞开辟了新的途径.

研究的目的:

  • 探索体细胞核转移 (SCNT) 和诱导多能干细胞 (iPSCs) 的潜力,以创造功能性雌激素.
  • 检查使用体细胞在配体生成对韦斯曼屏障理论的含义.

主要方法:

  • 身体细胞核转移 (SCNT) 程序.
  • 诱导多能干细胞 (iPSC) 的生成和分化.
  • 从重新编程的体细胞中获得的配体功能评估.

主要成果:

  • SCNT和iPSC技术显示出从体细胞中产生功能性性子细胞的前景.
  • 这些方法涉及对体细胞的直接使用,这似乎绕过或挑战了对韦斯曼屏障的传统理解.

结论:

  • SCNT和iPSC代表了生殖生物学领域的重大进展.
  • 从体细胞中成功生成性质细胞需要在现代再生医学和生殖技术的背景下对韦斯曼屏障进行重新评估.