葡萄糖受体的阻塞诱导α细胞的高分泌通过超氨基酸血症在小鼠

Jianxin Jia1,2, Xuanxuan Bai1,3, Qi Kang1,2

  • 1State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences and School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China.

Nature communications
|March 13, 2025
PubMed
概括

葡萄糖受体阻塞可以改善血糖控制,但会引起副作用. 这项研究表明,阿尔法细胞中的VGF上调有助于通过影响葡萄糖成熟而导致高葡萄糖血症.

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