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Updated: May 22, 2025

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
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饥饿诱导的HBP代谢重编程和STAM2 O-GlcNAcylation促进了膀癌的转移

Zhenwei Feng1,2, Yuhua Mei1,2, Haonan Chen1

  • 1Department of Urology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuan Jiagang, Yuzhong District, Chongqing, 400010, China.

Scientific reports
|March 13, 2025
PubMed
概括

谷氨胺-果糖-6-酸氨基转移酶1 (GFAT1) 通过增加STAM2的O-GlcNAcylation来驱动膀癌转移. 抑制GFAT1和O-GlcNAcylation为膀癌进展提供了一个潜在的治疗策略.

关键词:
这是一种O-GlcNAcylation.膀癌是一种癌症.转移 转移 转移 转移在STAM2中,STAM2是STAM2.

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