对比硫酸盐与2L聚乙烯糖醇电解质洗溶液用于结肠镜的肠道清洗功效:一项前性观察性研究
Jing Shan1, Yang Su2,3, Dan Luo2,3
1Department of Gastroenterology, Affiliated Hospital of Southwest Jiaotong University, The Third People's Hospital of Chengdu, No. 82 Qinglong Street, Qingyang District, Chengdu, 610014, Sichuan, China. tulip-sj@163.com.
皮科硫酸盐 (PICO) 和2L聚乙烯糖醇电解质洗液 (2L PEG-ELS) 在结肠镜肠道准备中表现出相似的疗效. 这两种方案都是安全有效的,而PICO在特定的肠道部分的得分略有提高.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 结肠直肠健康 结肠直肠健康
背景情况:
- 低容量肠道制剂对于有效的结肠镜检查至关重要.
- 对比硫酸盐 (PICO) 和2L聚乙烯糖醇电解质洗液 (2L PEG-ELS) 对于优化患者准备很重要.
研究的目的:
- 为了比较肠道清洁的有效性,不良反应和患者对PICO与2L PEG-ELS的遵守.
- 在中国人群中评估这两种低体积肠道制备方案的性能.
主要方法:
- 一个单一中心的前性观察性试验,涉及5423名接受结肠镜检查的患者.
- 使用波士顿肠道制备量表 (BBPS) 评估肠道清洁.
- 评估聚检测率,不良事件,以及患者愿意重复手术的情况.
主要成果:
- 在PICO和2L PEG-ELS之间,在适当的肠道清洁率 (92.2%与91.3%) 或聚检测率 (42.2%与45.5%) 中没有显著差异.
- 皮科组对全结肠和右结肠的BBPS得分明显更好.
- 2 L PEG-ELS组报告了更多的恶心,而PICO组报告了更多的睡眠障碍;两者的重复意愿都很高.
结论:
- 在中国人群中,PICO和2L PEG-ELS都是安全有效的肠道准备选项,用于结肠镜检查.
- 与2L PEG-ELS相比,PICO在某些部分显示出更高的肠道清洁得分.
- 患者的耐受性和愿意重复手术的意愿在两种方案中都是相似的.
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