在肯尼亚进行多站点实用因数临床试验中,试点实施短消息服务,用于随机化
Mercy Chepkirui1,2,3, Dennis Kimego4, Charles Nzioki5
1Epidemiology and Demography Department, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya. Mercy.Chepkirui@lstmed.ac.uk.
Pilot and feasibility studies
|March 13, 2025
概括
短信服务 (SMS) 随机化为临床试验参与者分配的传统方法提供了一个低成本,准确和可行的替代方案. 这种基于手机的方法在试点研究中被证明是用户友好和高效的.
科学领域:
- 临床试验方法论 临床试验方法论
- 医疗信息学 医疗信息学
- 移动健康 (mHealth) 服务提供商
背景情况:
- 传统的密封信封随机化容易受到操纵和损坏.
- 基于Web的随机化是昂贵的,需要可靠的互联网接入.
- 短信服务 (SMS) 随机化提供了一个潜在的低成本,强大的替代方案,特别是在资源有限的环境中.
研究的目的:
- 开发和评估基于SMS的方法,用于在临床试验中随机分配治疗.
- 评估SMS随机化在现实环境中的可行性,准确性和效率.
主要方法:
- 开发了一个SMS系统,使用参与者标识符和试验参数进行随机分配.
- 使用纯文本消息或Android应用程序来编写消息.
- 通过分配准确性检查,SMS延迟测量和用户反调查来评估可行性.
主要成果:
- 成功地随机选择了218名参与者,分配准确率为100%.
- 短信的中位延迟时间为22秒,证明了快速分配.
- 用户反表明,该系统易于使用和高效.
结论:
- 短信随机化是一种实用,用户友好和准确的临床试验分配技术.
- 该方法是可行的,并提供了一个可行的替代方案,特别是在互联网基础设施有限的地方.
关键词:
分配隐藏的分配隐藏方式临床试验中的临床试验.数字随机化的数字随机化隐藏信封的隐藏方式在信封中随机选择.移动SMS随机化随机化简单的文本消息传递.随机对照试验是随机对照试验.特别突击队的特种部队.更多相关视频
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